Friday, July 23, 2010

Obstetrics


Obstetrics (from the Latin obstare, "to stand by") is the surgical specialty dealing with the care of women and their children during pregnancy (prenatal period), childbirth and the postnatalperiod. Midwifery is the non-surgical equivalent. Veterinary obstetrics is the same concept forveterinary medicine. Almost all modern obstetricians are also gynaecologists.

Prenatal care

Prenatal care is important in screening for various complications of pregnancy. This includes routine office visits with physical exams and routine lab tests:

[edit]First trimester

genetic screening for downs syndrome (trisomy 21) and trisomy 18 the national standard in the United States is rapidly evolving away from the AFP-Quad screen for downs syndrome- done typically in the second trimester at 16–18 weeks. The newer integrated screen (formerly called F.A.S.T.E.R for First And Second Trimester Early Results) can be done at 10 plus weeks to 13 plus weeks with an ultrasound of the fetal neck (thick skin is bad) and two chemicals (analytes) Papp-a and bhcg (pregnancy hormone level itself). It gives an accurate risk profile very early. There is then a second blood screen at 15 to 20 weeks which refines the risk more. The cost is higher than an afp-quad screen due to the ultrasound and second blood test but it is quoted to have a 92% pick up rate.

[edit]Second trimester

  • MSAFP/quad. screen (four simultaneous blood tests) (maternal serum alpha-fetoprotein; inhibin; estriol; bhcg or free bhcg) - elevations, low numbers or odd patterns correlate with neural tube defect risk and increased risks of trisomy 18 or trisomy 21
  • Ultrasound either abdominal or trannsvaginal to assess cervix, placenta, fluid and baby
  • Amniocentesis is the national standard for women over 35 or who reach 35 by mid pregnancy or who are at increased risk by family history or prior birth history

[edit]Third trimester

  • Hematocrit (if low, mother will receive iron supplementation)
  • Glucose loading test (GLT) - screens for gestational diabetes; if > 140 mg/dL, a glucose tolerance test (GTT) is administered; a fasting glucose > 105 mg/dL suggests gestational diabetes.
Most doctors do a sugar load in a drink form of 50 grams of glucose in cola, lime or orange and draw blood an hour later (plus or minus 5 minutes) ; the standard modified criteria have been lowered to 135 since the late 1980s

[edit]Antenatal record

On the first visit to her obstetrician or midwife, the pregnant woman is asked to carry out the antenatal record, which constitutes a medical history and physical examination. On subsequent visits, the gestational age (GA) is rechecked with each visit.
Symphysis-fundal height (SFH; in cm) should equal gestational age after 20 weeks of gestation, and the fetal growth should be plotted on a curve during the antenatal visits. The fetus is palpated by the midwife or obstetrician using Leopold maneuver to determine the position of the baby. Blood pressure should also be monitored, and may be up to 140/90 in normal pregnancies. High blood pressure indicates hypertensionand possibly pre-eclampsia, if severe swelling (edema) and spilled protein in the urine are also present.
Fetal screening is also used to help assess the viability of the fetus, as well as congenital problems. Genetic counseling is often offered for families who may be at an increased risk to have a child with a genetic condition. Amniocentesis at around the 20th week is sometimes done for women 35 or older to check for Down's Syndrome and other chromosome abnormalities in the fetus.
Even earlier than amniocentesis is performed, the mother may undergo the triple test, nuchal screening, nasal bone, alpha-fetoproteinscreening and Chorionic villus sampling, also to check for disorders such as Down Syndrome. Amniocentesis is a prenatal genetic screening of the fetus, which involves inserting a needle through the mother's abdominal wall and uterine wall, to extract fetal DNA from the amniotic fluid. There is a risk of miscarriage and fetal injury with amniocentesis because it involves penetrating the uterus with the baby still in utero.

[edit]Imaging





A dating scan at 12 weeks.
Imaging is another important way to monitor a pregnancy. The mother and fetus are also usually imaged in the first trimester of pregnancy. This is done to predict problems with the mother; confirm that a pregnancy is present inside the uterus; estimate the gestational age; determine the number of fetuses and placentae; evaluate for an ectopic pregnancy and first trimester bleeding; and assess for early signs of anomalies.
X-rays and computerized tomography (CT) are not used, especially in the first trimester, due to theionizing radiation, which has teratogenic effects on the fetus. No effects of magnetic resonance imaging (MRI) on the fetus have been demonstrated,[1] but this technique is too expensive for routine observation. Instead, ultrasound is the imaging method of choice in the first trimester and throughout the pregnancy, because it emits no radiation, is portable, and allows for realtime imaging.
Ultrasound imaging may be done at any time throughout the pregnancy, but usually happens at the 12th week (dating scan) and the 20th week (detailed scan).
A normal gestation would reveal a gestational sac, yolk sac, and fetal pole. The gestational age can be assessed by evaluating the mean gestational sac diameter (MGD) before week 6, and the crown-rump length after week 6. Multiple gestation is evaluated by the number ofplacentae and amniotic sacs present.

[edit]Complications and emergencies

The main emergencies include:
  • Ectopic pregnancy is when an embryo implants in the Fallopian tube or (rarely) on the ovary or inside the peritoneal cavity. This may cause massive internal bleeding.
  • Pre-eclampsia is a disease which is defined by a combination of signs and symptoms that are related to maternal hypertension. The cause is unknown, and markers are being sought to predict its development from the earlist stages of pregnancy. Some unknown factors cause vascular damage in the endothelium, causing hypertension. If severe, it progresses to eclampsia, where a convulsions occur, which can be fatal. Preeclamptic patients with the HELLP syndrome show liver failure and Disseminated intravascular coagulation (DIC).
  • Placental abruption where the patient can bleed to death if not managed appropriately.
  • Fetal distress where the fetus is getting compromised in the uterine environment.
  • Shoulder dystocia where one of the fetus' shoulders becomes stuck during vaginal birth, especially in macrosomic babies of diabetic mothers.
  • Uterine rupture can occur during obstructed labor and endangered fetal and maternal life.
  • Prolapsed cord refers to the prolapse of the fetal cord during labor with the risk of fetal suffocation.
  • Obstetrical hemorrhage may be due to a number of factors such as placenta previa, uterine rupture of tears, uterine atony, retained placenta or placental fragments, or bleeding disorders.
  • Puerperal sepsis is a progressed infection of the uterus during or after labor.

[edit]Fetal assessments

Ultrasound is routinely used for dating the gestational age of a pregnancy from the size of the fetus, the most accurate dating being in first trimester before the growth of the fetus has been significantly influenced by other factors. Ultrasound is also used for detecting congenital anomalies (or other fetal anomalies) and determining the biophysical profiles (BPP), which are generally easier to detect in the second trimester when the fetal structures are larger and more developed. Specialised ultrasound equipment can also evaluate the blood flow velocity in the umbilical cord, looking to detect a decrease/absence/reversal or diastolic blood flow in the umbilical artery.
Other tools used for assessment include:

[edit]Childbirth

[edit]Induction

Induction is a method of artificially or prematurely stimulating labour in a woman. Reasons to induce can include pre-eclampsia, the birth mass, diabetes, and other various general medical conditions, such as renal disease. Induction may occur any time after 34 weeks of gestation if the risk to the fetus or mother is greater than the risk of delivering a premature fetus regardless of lung maturity. If a woman does not eventually labour by 41–42 weeks, induction may be performed, as the placenta may become unstable after this date.[citation needed]
Induction may be achieved via several methods:

[edit]Labor

During labor itself, the obstetrician/doctor/intern/medical student under supervision may be called on to do a number of tasks. These tasks can include:
  • Monitor the progress of labor, by reviewing the nursing chart, performing vaginal examination, and assessing the trace produced by a fetal monitoring device (the cardiotocograph)
  • Accelerate the progress of labor by infusion of the hormone oxytocin
  • Provide pain relief, either by nitrous oxide, opiates, or by epidural anesthesia done by anaesthestists, an anesthesiologist, or a nurse anesthetist.
  • Surgically assisting labor, by forceps or the Ventouse (a suction cap applied to the fetus' head)
  • Caesarean section, if there is an associated risk with vaginal delivery, as such fetal or maternal compromise supported by evidence and literature. Caesarean section can either be elective, that is, arranged before labor, or decided during labor as an alternative to hours of waiting. True "emergency" Cesarean sections include abruptio placenta, and are more common in multigravid patients, or patients attempting a Vaginal Birth After Caeserean section (VBAC).

[edit]Postnatal

A woman in the Western world who is delivering in a hospital may leave the hospital as soon as she is medically stable and chooses to leave, which can be as early as a few hours postpartum, though the average for spontaneous vaginal delivery (SVD) is 1–2 days, and the average caesarean section postnatal stay is 3–4 days. During this time the mother is monitored for bleeding, bowel and bladder function, and baby care. The infant's health is also monitored.[2]

[edit]Salary

The salary of a obstetrician varies by country. In the United States, the salary ranges from $200,000 to $339,738.
Country


Annual salary (US$)
United Kingdom187,771[3]
United Arab Emirates231,809[4]
United States236,411


Obstetric ultrasonography



Obstetric sonography (ultrasonography) is the application of medical ultrasonography to obstetrics, in which sonography is used to visualize the embryoor foetus in its mother's uterus (womb). The procedure is often a standard part ofprenatal care, as it yields a variety of information regarding the health of the mother and of the fetus, as well as regarding the progress of the pregnancy.
Obstetric sonogram of a fetus at 16 weeks. The bright white circle center-right is the head, which faces to the left. Features include the forehead at 10 o'clock, the left ear toward the center at 7 o'clock and the right hand covering the eyes at 9:00.


Types

Traditional obstetric sonograms are done by placing a transducer (a device that converts one type of energy into another) on the abdomen of the pregnant woman. One variant is a transvaginal sonography is done with a probe placed in the woman's vagina. Transvaginal scans usually provide clearer pictures during early pregnancy and in obese women. Also used is Doppler sonography which detects the heartbeat of the fetus. Doppler sonography can be used to evaluate the pulsations in the fetal heart and bloods vessels for signs of abnormalities.[1]

[edit]Early pregnancy

The gestational sac can sometimes be visualized as early as four and a half weeks of gestation (approximately two and a half weeks after ovulation) and the yolk sac at about five weeks gestation. The embryo can be observed and measured by about five and a half weeks. Theheartbeat may be seen as early as 6 weeks, and is usually visible by 7 weeks gestation.[1][2]

[edit]Dating and growth monitoring

Gestational age is usually determined by the date of the woman's last menstrual period, and assuming ovulation occurred on day fourteen of the menstrual cycle. Sometimes a woman may be uncertain of the date of her last menstrual period, or there may be reason to suspect ovulation occurred significantly earlier or later than the fourteenth day of her cycle. Ultrasound scans offer an alternative method of estimating gestational age. The most accurate measurement for dating is the crown-rump length of the fetus, which can be done between 7 and 13 weeks of gestation. After 13 weeks gestation, the fetal age may be estimated by the biparietal diameter (the transverse diameter of the head), the head circumference, the length of the femur (the longest bone in the body), and the many more fetal parameters that have been measured and correlated with age over the last 30 years. Dating is more accurate when done earlier in the pregnancy; if a later scan gives a different estimate of gestational age, the estimated age is not normally changed but rather it is assumed the fetus is not growing at the expected rate.[1]
Not useful for dating, the abdominal circumference of the fetus may also be measured. This gives an estimate of the weight and size of the fetus and is important when doing serial ultrasounds to monitor fetal growth.[1]

[edit]Fetal sex determination

Sonogram of male fetus, with scrotum and penis in center of image
The sex of the baby can usually be determined by ultrasound at any time after 16 weeks, often at the dating scan around 20 weeks into the pregnancy depending upon the quality of the sonographic machine and skill of the operator. This is also the best time to have an ultrasound done as most infants are the same size at this stage of development. Depending on the skill of the sonographer, ultrasound may suffer from a high rate of false negatives and false positives. This means care has to be taken in interpreting the accuracy of the scan.

[edit]Ultrasonography of the cervix

Fetus at 14 weeks (profile)
Obstetric sonography has become useful in the assessment of the cervix in women at risk forpremature birth. A short cervix preterm is undesirable: At 24 weeks gestation a cervix length of less than 25 mm defines a risk group for preterm birth, further, the shorter the cervix the greater the risk.[3] It also has been helpful to use ultrasonography in women with preterm contractions, as those whose cervix length exceed 30 mm are unlikely to deliver within the next week.[4]

[edit]Abnormality screening

In some countries, routine pregnancy sonographic scans are performed to detect developmental defects before birth. This includes checking the status of the limbs and vital organs, as well as (sometimes) specific tests for abnormalities. Some abnormalities detected by ultrasound can be addressed by medical treatment in utero or by perinatal care, though indications of other abnormalities can lead to a decision regarding abortion.
Perhaps the most common such test uses a measurement of the nuchal translucency thickness ("NT-test", or "Nuchal Scan"). Although 91% of fetuses affected by Down syndrome exhibit this defect, 5% of fetuses flagged by the test do not have Down syndrome.
Ultrasound may also detect fetal organ anomaly. Usually scans for this type of detection are done around 18 to 20 weeks of gestational age.

[edit]History

Scottish physician Ian Donald was one of the pioneers of medical use of ultrasound. His article "Investigation of Abdominal Masses by Pulsed Ultrasound" was published in The Lancet in 1958. Donald was Regius Professor of Midwifery at the University of Glasgow.[5]
In 1962, after about two years of work, Joseph Holmes, William Wright, and Ralph Meyerdirk developed the first compound contact B-mode scanner. Their work had been supported by U.S. Public Health Services and the University of Colorado. Wright and Meyerdirk left the university to form Physionic Engineering Inc., which launched the first commercial hand-held articulated arm compound contact B-mode scanner in 1963.[6] This was the start of the most popular design in the history of ultrasound scanners.
Obstetric ultrasound has played a significant role in the development of diagnostic ultrasound technology in general. Much of the technological advances in diagnostic ultrasound technology are due to the drive to create better obstetric ultrasound equipment. Acuson Corporation's pioneering work on the development of Coherent Image Formation helped shape the development of diagnostic ultrasound equipment as a whole.

[edit]Safety issues

Current evidence indicates that diagnostic ultrasound is safe for the unborn child, unlike radiographs, which employ ionizing radiation. However, no randomized controlled trials have been undertaken to test the safety of the technology, and thus ultrasound procedures are generally not done repeatedly unless medically indicated.
A 2006 study on mice exposed to ultrasound showed neurological changes in the exposed fetuses. Some of the rodent brain cells failed to migrate to their proper position and remained scattered in incorrect parts of the brain.[7]
It has been shown that Low Intensity Pulsed Ultrasound does have a localized effect on growth in human beings. The 1985 FDA-allowed maximum power of 180 milliwatts per square cm [8] is well under the levels used in therapeutic ultrasound, but still higher than the 30-80 milliwatts per square cm range of the Statison V veterinary LIPUS device.[9] LIPUS has been shown to affect tissue growth in as little as 20 minutes of time with repeated daily applications. Adding to the similarity, LIPUS and medical ultrasound both operate in the 1 to 10MHz range.
While the benefits of medical ultrasound probably outweigh any risks, vanity uses such as making 3D ultrasound movies without a doctors order present an obviously unnecessary but unknown risk to a developing fetus. Clinical guidelines produced by the Society of Obstetricians and Gynaecologists of Canada recommend against the non-medical use of fetal ultrasound.[10]

List of obstetric topics

Obstetrics is the study of the reproductive process within the female body, including fertilization, pregnancy and childbirth.

Basic obstetric terms

[edit]Complications of pregnancy and childbirth

Childbirth and obstetrics in antiquity

Traditionally obstetrics is defined as the surgical specialty dealing with the care of a woman and her offspring during pregnancy, childbirth and the puerperium, although in Antiquity surgical intervention did not exist. Without the presence of surgical technology an alternative was necessary. In 2nd century AD, physician Soranus wrote a text on gynecology introducing the occupation of the midwife.
Midwifery and obstetrics are distinctly different but overlap in medical practice that focuses on pregnancy and labor. Midwifery emphasizes the normality of pregnancy along with the reproductive process.

Midwifery

Midwifery flourished in the 2nd century AD, in the beginning of the Hippocratic Corpus. Soranus states that for a woman to be an eligible midwife she must be “A suitable person…must be literate to be able to comprehend the art through theory too. She must have her wits about her so that she may easily follow what is said and what is happening. She must have a good memory to retain the imparted instructions (for knowledge arises from memory of what has been grasped). She must love work, to preserve through all vicissitudes (for a woman who wishes to acquire such vast knowledge needs manly patience).
The most qualified midwife would be trained in all branches of therapy. She should be able to prescribe hygienic regulations for her patients, observe the general and individual features of the case, give advice by recalling from previous knowledge what medical decisions would work in every case and to be reassuring to her patients. It is not necessary for her to have had a child to deliver another woman’s child, but it is good if she has been in labor to enhance sympathy with the mother.
To obtain good midwifery habits, she will be well disciplined and always sober, have a quiet disposition sharing many life secrets, must not be greedy for money, be free of superstition to not overlook salutary measures, keeping her hands soft by staying away from wool-working as this may harden her hands and use ointments to acquire softness. She too needs to be respectable, the people of the household will have to trust her within their household, may not be handicapped in the performance of her work. Long and slim fingers with short nails are necessary to touch deep-lying inflammation without causing too much pain. Midwives that acquire of all these will be the best midwives[1].

[edit]Labor and delivery

Midwifery and the process of labor and delivery in antiquity go hand in hand. Hospitals did not exist so delivery took place in the home of the expectant mother with a midwife and the presence of other females to aid the midwife.
Superstitions and religion played a major role in antiquity including childbirth. Women in labor called upon the goddess Artemis who had the ability to bring new life into the world and take it away. Though she remained a virgin herself, it was said that she witnessed the pain of her mother during the birth of her brother, Apollo, and immediately assumed the position of midwife. If a woman died while during childbirth, her clothes were taken to the temple of Artemis due to the fact her death was attributed to her[2]. If the birth was successful, the mother would make a thank-offering of some of her clothes to the goddess as well[3].
Herbs and plants were used heavily in the delivery process also with strong ties to superstition. For example, a drink sprinkled with powdered sow’s dung was given to relieve labor pain and fumigation with the fat from a hyena was thought to produce immediate delivery[4]. Most of these practices had little to no medical efficacy, but they did probably provide some placebo effect. These superstitious practices were very common and required little or no medical training.
Significant advances were made in child bearing with the introduction of the Hippocratic Corpus in the 3rd century BCE, though this document still proved to implement many ideas concerning superstitions. Physician, Galen, also provided much advancement in medicine for women in the late 1st century CE, though he focused mostly on specific diseases with only some aspects of labor mentioned. Physician Soranus, who wrote several texts on gynecology in the 2nd century CE, has proven to be the most eminent authority on childbirth and obstetrics in antiquity.
Soranus described three main stages of pregnancy: conception which regarded keeping the male seed within the womb, pica which occurred 40 days into pregnancy and included symptoms of nausea and cravings for extraordinary foods. During this phase women were also instructed to exercise and sleep more to build up strength as preparation for the labor process. Lastly the last stage of pregnancy was described being the labor and the process of delivery. In preparation for labor, the woman was advised to bath in wine and sweet-water baths to calm her mind before delivery. Her belly was then rubbed with oils to decrease the appearance of stretch marks and her genitals were anointed with herbs and injected with softeners such as goose fat[5].
The role of the midwife was very important during the process of childbirth and Soranus described her role in great detail. For example, the midwife was to have certain tools to ensure a safe delivery including: clean olive oil, sea sponges, pieces of wool bandages to cradle the infant, a pillow, strong smelling herbs in case of fainting, and a birthing stool[6].
The midwife would ready her supplies as labor began. During the labor process, the mother would lay on her back on a hard, low bed with support under her hips. Her thighs were parted with her feet drawn up. Gentle massage was implemented to ease labor pains as cloths soaked in warm olive oil were laid over her stomach and genital area. Against the woman's sides were placed hot compresses in the form of warm oil-filled bladders[7].
During the actual birth, the mother would be moved to the birthing stool where she was seated with a midwife in front of her and female aids standing at her sides. In a normal headfirst delivery, the cervical opening was stretched slightly, and the rest of the body was pulled out. Soranus instructed the midwife to wrap her hands in pieces of cloth or thin papyrus so that the slippery newborn did not slide out of her grasp[8].

[edit]Caesarian sections

The word “caesarian” possibly derives from the ancient Roman ruler Julius Caesar, because it was believed that Caesar was delivered through this procedure [9]. However, this is probably based more on tradition and myth than historical accuracies. Another possibility for the etymology of the word “caesarian” is the Latin word caedere, meaning “to cut”[10].
This practice is probably much older than Caesar, but C-sections as performed by the Romans were to rescue the baby from a dying or already dead mother (performed post-mortem)[11].
Evidence suggests that Jews in ancient Rome practiced C-sections on living mothers who were not in danger of dying[12]. Evidence of these procedures is found in several collections of ancient Roman Rabbis (the most famous of which is called the Mishnah[13]).
Greeks and Egyptians did not perform C-sections post-mortem or on living mothers. However, Greeks would have had at least some knowledge of the caesarian operation/ procedure. The Greek god Aesclepius was fabled to have been extracted from his mother’s womb through this process[14].
Other than the evidence of Jews practicing C-sections in antiquity (very little in ancient Rome, even less in ancient Greece), not much more evidence exists regarding caesarian-operation birth. One reason could have been that C-sections were not performed very often because of medical complications or superstitions surrounding C-sections.
In early Christian Rome, C-sections were almost non-existent[15]. Loss of skill is a possibility for the lack of C-sections. Infant mortality rates were high in antiquity, so C-sections certainly could have been useful. However, early Christian doctors could have disregarded C-sections as a socially acceptable surgery because of religious beliefs[16].
The lack of education for women (who would have been the most knowledgeable about childbirth procedures) and the social norm that women remained in the private sphere of life (as opposed to public) could also have contributed to a shortage of C-sections[17]. Midwives were the primary persons involved in the childbirth process. Midwives were women, and were not actually physicians. They did not record their medical practices in writing like Soranus or Galen. Thus, C-sections could have potentially occurred on a fairly regular basis, accounts were just not recorded.
Disease, need for secrecy, and social discouragement could also have been factors that lead to the decline in C-sections among early Christians in Rome (for almost no evidence exists for C-sections in the Christian world until the 10th c.)[18].

[edit]Death and childbirth

Mortality is considered to have been quite high in antiquity, due to a few factors: a lack of sanitation and hygienic awareness, no understanding of micro-organisms, and a dearth of effective drugs all contributed. In the context of childbirth, however, maternal and infant mortality were seriously raised by modern standards. This inflation resulted from the toll childbirth took on women, and the increased risk of infection following labor. Infants in the modern era are fragile compared to adults, and the lack of sanitation mentioned above contributed further to this fragility.
Maternal
Maternal mortality figures are available only through comparison. While well-attested in the sense that sources are not lacking, all evidence is anecdotal and difficult to extrapolate valid statistics from. Therefore, maternal mortality is thought to be comparable with figures for similar, but much later, societies with more surviving records, such as eighteenth-century rural England, where maternal mortality averaged 25 per 1000 births[19].
Infant
The question of infant mortality in antiquity is complicated by infanticide and exposure, neither of which reflect on medical ability during the period, though both remove children from family records. The former does this through intentional death of the child, and the latter through abandonment, and possible death. These reflect instead on social conditions and norms. While valuable, this is not the information sought, and scholars having painstakingly attempted to eliminate the noise from their inquiries[20].
While it is difficult to construct actual figures of the infant mortality rate in antiquity, comparisons have been made between ancient societies and modern non-industrialized societies. The figures suggested for these are then compared with those of modern industrialized societies to put them in perspective. While infant mortality is less than 10 per 1000 in modern industrialized societies, non-industrialized societies display rates from 50 to 200+ per 1000. Scholarship using model life tables and assuming life expectancy at birth of 25 years produces the figure of 300 per 1000 for Roman society[21
















































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